VThunter

a database for single-cell screening of virus target cells in animal kingdom

Pangolin

Scientific Name: Manis javanica

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Pholidota-> Manidae-> Manis

Porcine reproductive and respiratory syndrome virus

Family: Arteriviridae

Receptor: SIGLEC1

Receptor SIGLEC1 information

Summary: This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008] [NCBI] [Proteinatlas]

Data Source

Data set information

Project	Date	Technology	Tissue	Condition	Cell	PMID/DOI
Vthunter_0036	2021.04	10X Genomics	Esophagus	Normal	24581	Link
Vthunter_0037	2021.04	10X Genomics	Heart	Normal	12958	Link
Vthunter_0039	2021.04	10X Genomics	LargeIntestine	Normal	3328	Link
Vthunter_0040	2021.04	10X Genomics	Liver	Normal	5694	Link
Vthunter_0041	2021.04	10X Genomics	Lung	Normal	13720	Link
Vthunter_0042	2021.04	10X Genomics	Spleen	Normal	3207	Link
Vthunter_0043	2021.04	10X Genomics	Stomach	Normal	12485	Link

Featureplot of receptors

mRNA expression of SIGLEC1 in human tissues [NCBI]

Expression: Broad expression in placenta (RPKM 8.2), spleen (RPKM 6.4) and 20 other tissues

Protein expression of SIGLEC1 in human tissues [Proteinatlas]